Today,
15 million people have diabetes in North America, plus another
23 million in Western Europe. Those numbers continue to grow
by more than 4% per year. Each year up to 24,000 adults lose
their sight because of diabetic complications. In fact, one out
of every ten health care dollars spent in the United States is
spent on diabetes and its complications.Once
approval is granted, we expect the total addressable market for
our target regions (North America and Western Europe) will exceed
$10 billion in the first year.
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A cataract is a clouding of the eye's natural
lens, which lies behind the iris and the pupil. The lens works
much like a camera lens, focusing light onto the retina at the
back of the eye. The lens also adjusts the eye's focus, letting
us see things clearly both up close and far away. The lens is mostly
made of water and protein. The protein is arranged in a precise
way that keeps the lens clear and lets light pass through it. As
we age, some of the protein may clump together and start to cloud
a small area of the lens. This is a cataract, and over time, it
may grow larger and cloud more of the lens, making it harder to
see.d
The
same eye drop that we are developing to combat diabetic retinopathy
will also slow down or prevent diabetic cataract
formation. Cataract surgery is the most common type of surgery
in the United
States. The daily use of our eye drop, can slow down or prevent
the development of diabetic cataracts, potentially avoiding costly
surgery.
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